From PK-PD to COUNTDOWN: Multidisciplinary studies on schistosomiasis in Africa

On Friday the 20 November Russell Stothard will be presenting at the London School of Hygiene and Tropical Medicine in one of the regular seminars of the Department of Immunology and Infection.

Russell will discuss contemporary research on schistosomiasis and draw attention to the pioneering early role of the London School’s first helminthologist, Robert Leiper, who uncovered the lifecycle of the African schistosome 100 years ago. Russell’s recent work in Uganda has drawn attention to a significant burden of disease in pre-school children, and he will present the case as to why expanded access to praziquantel treatment is needed now. Ongoing pharmacokinetic and pharmacodynamic (PK-PD) suggests that higher doses of praziquantel may be required.  Russ will close showing how implementation research, as framed within the DFID-funded COUNTDOWN consortium, is playing an important role in accelerating towards WHO 2020 NTD targets.

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